Analyzing plexDIA data

 

Data pipeline

A pipeline for analyzing plexDIA data and reproducing the analysis by Derks et al are available at the plexDIA GitHub repository.

 

Searching plexDIA data

Searching plexDIA data with DIA-NN is described in this tutorial.

 

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Detailed methods can be found at:

Derks, J., Leduc, A., Wallmann, G. et al. Increasing the throughput of sensitive proteomics by plexDIA. Nat Biotechnol (2022). 10.1038/s41587-022-01389-w, Preprint